• Plasmid DNA Preparation

Creation of viral vectors for gene therapy applications requires significant volumes of plasmid DNA. Synplogen is developing microbial cultivation processes that result in high plasmid DNA yield, ensuring you always have enough plasmid DNA on hand.

Gene amplification

Synplogen uses E. coli and B. subtilis as its primary organisms for amplification.
Synplogen can provide flask or fermenter-scale solutions depending on your volume needs.

  • Escherichia coli

    Tried and true solution for plasmid DNA in the pharmaceutical industry

    High plasmid DNA yield

    Bacillus subtilis

    Significant Synplogen know-how

    Endotoxin-free

    Genes can be modified as necessary

  • 利⽤する微⽣物

Flow

Select "Gene therapy vector preparation/characterization" from the contact form and submit your request details.

Select "Gene therapy vector preparation⁄characterization" from the contact form and submit your request details.

You will be contacted shortly by a Synplogen representative. Please also provide information regarding the nucleic acid and vector.
(An NDA/CDA can be signed if necessary.)

You will be contacted shortly by a Synplogen representative. Please also provide information regarding the nucleic acid and vector.

Synplogen's technical staff and safety committee will determine whether your request can be accepted.

Synplogen's technical staff and safety committee will determine whether your request can be accepted.

If your request can be accepted, you will be provided with an estimate for the services. After receiving confirmation of your order, the requested work will begin.

If your request can be accepted, you will be provided with an estimate for the services. After receiving confirmation of your order, the requested work will begin.

*For joint R&D inquiries and technical questions,
please use the same contact form.
(Planned start of high-volume plasmid DNA preparation service in Spring, 2021)

Disclaimers

  • Viral vectors provided by Synplogen may only be used for research and may not be used for clinical or diagnostic applications. If the provided samples are used for anything other than research, Synplogen accepts no liability for any loss or damage that may arise from such use.
  • If viral vectors are necessary for commercial use, please make this clear in your inquiry. A licensing agreement may be necessary.
  • Follow all direction and guidelines for treatment and handling of viral vectors which are provided by law, ordinance (laws governing use of GMOs/LMOs for the protection of biodiversity, local regulations for the appropriate biosafety level/containment measures, etc.) or safety authority (government body or affiliated organization).